What is hereditary deafness? What are the major factor that leads to deafness?

 


Deafness can be hereditary and start at birth or develop later in life. One of these types of hereditary deafness is DFNA9, which is caused by a mutation in a gene called DFNA9. Normal people inherit two copies of this gene from their mother and father.

The Cx26 gene is responsible for most cases of hereditary hearing loss. This gene is responsible for 50% of non-syndromic hearing loss. Mutations in this gene cause various auditory phenotypes. In congenital deafness, hair cells die due to a genetic defect. In the late-onset hearing loss, endocochlear potential decreases, and the cochlear hair cells are degenerating. The Cx26 gene is responsible for most cases of hereditary hearing loss. This gene is responsible for 50% of non-syndromic hearing loss. Mutations in this gene cause various auditory phenotypes. In congenital deafness, hair cells die due to a genetic defect.

Some labs offer custom-designed panels for the analysis of the genetic codes of patients with non-syndromic hereditary hearing loss. Such panels are designed to identify copy number variants in genes that contribute to the symptoms of hereditary hearing loss. Because these variants can affect a wide range of genes, multigene panels are essential for hereditary hearing loss diagnosis. This is because they can identify small copy number variants, which may be missed in conventional genetic testing. Recent product launches and approvals is expected to boost the global hereditary deafness market growth.

Despite these genetic disorders, researchers are making progress in the treatment of the disorder. Researchers have discovered a gene responsible for the development of the auditory pathway in mice. This gene has a role in hereditary deafness, and the researchers believe that it will ultimately lead to new treatments for the condition.

The genetics of hereditary hearing loss is extremely complex. Molecular biology has helped researchers identify several genes responsible for the condition.  Hereditary deafness is classified as a recessive genetic disorder, which means that individuals who carry two copies of the mutated gene will be deaf. The carriers of the normal gene will not become deaf, although they are carriers of the mutated copy.

 

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